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Benninger 2010 AAAI M, Farrar JR, Blaiss M, et al. Evaluating approved medications to treat allergic rhinitis in the United States: an evidence-based review of efficacy for nasal symptoms by class. Blackwell DL, Lucas JW, Clarke TC.

Summary health statistics for U. National Center for Health Statistics. Vital Health Stat 10 260. Bloom B, Jones LI, Freeman G. Vital Health Stat 10 258. Carson S, Lee N, Thakurta S.

Some people respond better to the older antihistamines than the newer ones. In addition, a patient might get relief from an older drug without much sedation. Good to note: Studies have found slowed reaction times among some people taking the older antihistamines, even when they denied feeling drowsy.

One concern is that could raise the risk for auto accidents and other incidents at home and work, although this link has not been clearly proven.

Do you have allergies, or is it something else. And sedation and drowsiness can still occur when taking the newer medications, especially at higher doses, although they are thought to be safer in this regard.

People with allergic disorders produce a substance known as immunoglobulin E, or IgE for short, when they are exposed to normally harmless substances, such as pollen, mold, animal dander, or certain medicines or foods.

These are actually antibodies that cause allergic reactions. An allergy is essentially an overreaction of the body, and the histamine can cause symptoms such as itchy and watery eyes, sneezing, hives, runny nose, asthmatic reactions, and a drop in blood pressure. This is why antihistamine treatments typically deal with this problem. There are cases where people suffer allergic symptoms during different seasons of the year, otherwise known as a spring, fall, or summer hay fever.