There were no clinical trials in patients with asthma to compare the effectiveness of Singulair when used in the morning compared to the evening. Now you can gain knowledge and insight about a drug treatment with Patient Discussions. The safety profile of Singulair in a 6-week, double-blind, placebo-controlled clinical study was generally similar to the safety profile in adults and pediatric patients 2 to 14 years of age. These doses were approximately and times the maximum recommended daily oral dose in adults, respectively, based on AUCs. Check drug classification singulair drug interactions. AU : S4 Prescription only. E-Cigarette Use May Up Bladder Cancer Risk. Saint Kitts and Nevis. Contact your doctor right away if asthma symptoms get worse or you have mood or behavior changes, anxiety, depression, or thoughts about suicide or hurting yourself.
Skip the missed dose and continue your regular dosing schedule. Whitehouse Station, NJ , USA DIRECTIONS FOR USE: See accompanying Package Insert. Continue to take montelukast even if you feel well. Report Problems to the Food and Drug Administration. We comply with the HONcode standard for trustworthy health information - verify here. The packet should not be opened until ready to use.
Migraine Triggers You Can Avoid. Have a Little Fun! The frequency of less common adverse events was comparable between Singulair and placebo. Safety and efficacy profiles in this age group are similar to those seen in adults [see Adverse Reactions 6. Montelukast demonstrated no evidence of mutagenic or clastogenic activity in the following assays: the microbial mutagenesis assay, the V mammalian cell mutagenesis assay, the alkaline elution assay in rat hepatocytes, the chromosomal aberration assay in Chinese hamster ovary cells, and in the in vivo mouse bone marrow chromosomal aberration assay. In vitro studies using human liver microsomes indicate that CYP3A4, 2C8, and 2C9 are involved in the metabolism of montelukast. There were no clinical trials in patients with asthma to compare the effectiveness of Singulair when used in the morning compared to the evening. Add Drug To My List.